Table 1.
Summary of clinical and epileptological patients’ data.
| Pts | Age at Seizure Onset (Years) | Age at Surgery (Years) | Anti-Seizure Medications | MRI Findings | Seizure Semiology | EEG Findings | Outcome | Neurologic Follow-Up (Years) | Post-Surgical Complications |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 0.3 | 1.5 | GVG | Right HME | Asymmetric spasms (left) | Continuous spikes/polyspikes and slow waves, with low voltage fast activity over the right hemisphere. | Engel Ia | 11 | Hydrocephalus |
| 2 | 0.5 | 2.9 | PB, ACTH, VPA, GVG, CLB, LEV | Right HME | Left tonic seizures and asymmetric spasms | Continuous periodic paroxysmal activity over the right posterior perisylvian region. | Engel Ia | 7 | Hydrocephalus |
| 3 | 0.1 | 0.3 | PB, GVG, ACTH, CBZ | Left HME | Right asymmetric spasms and tonic seizures | Pseudo-periodic paroxysmal pattern over the left hemisphere, mainly over temporal and parietal regions. | Engel Ia | 5 | No |
| 4 | 0.1 | 0.2 | VGB, PB, LEV | Right HME | Left clonic seizures | Continuous slow delta waves over the right occipital area, sometimes diffused over the homologous contralateral area. | Engel Ia | 5 | Left transverse venous sinus thrombosis. |
ASM: anti-seizure medications; CBZ: carbamazepine, CLB: clobazam, LEV: levetiracetam; HME: hemimegalencephaly; PB: phenobarbital; VGB: vigabatrin; VPA: valproic acid.