Figure 1.

PA inhibits the proliferation and anchorage-independent growth of gastric cancer cells. (A) The inhibitory effects of PA on proliferation in human gastric cancer cells and normal gastric epithelial cells were detected using MTT assays after treatment for 24–48 h. Inhibition rates (%) = (A_NC − A_PA)/A_NC × 100 A_NC: absorbance of reaction with without PA, and A_PA: absorbance of reaction with various concentrations of PA. (B) Effects of PA on colony formation in human gastric cancer cells treated for 14 days. (C) EdU-DNA assay was performed to detect the effects of PA on MGC-803 and BGC-823 cell proliferation after 18 h (Mean ± SEM, ns nonsignificant, *** p < 0.001, ** p < 0.01, * p < 0.05).