Table 2.
Relative variables for seizure recurrence estimated with a Cox proportional hazards model on univariable and multivariable Cox regression analysis.
| Variables | Univariable Analysis | Multivariable Analysis | ||||
|---|---|---|---|---|---|---|
| HR | p-Value | 95%CI | HR | p-Value | 95%CI | |
| Age at seizure onset | ||||||
| ≤4 years | 1.00 | |||||
| >4 years | 0.25 | 0.012 * | 0.08–0.74 | 0.94 | 0.939 | 0.20–4.43 |
| Duration of seizures | ||||||
| ≤4 years | 1.00 | |||||
| >4 years | 4.87 | 0.005 * | 1.63–14.56 | 4.32 | 0.016 * | 1.31–14.2 |
| IEDs | ||||||
| Regional | 1.00 | |||||
| Unilateral | 10.09 | 0.021 * | 1.41–72.09 | 4.91 | 0.130 | 0.63–38.47 |
| Bilateral | 12.09 | 0.002 * | 2.43–60.09 | 6.38 | 0.047 * | 1.03–39.64 |
| Nonspecific | 5.33 | 0.054 | 0.97–29.13 | 1.26 | 0.817 | 0.18–8.91 |
| MRI subtype | ||||||
| Type 1 | 1.00 | |||||
| Type 2 | 0.00 | 0.999 | 0.00–Inf | 0.00 | 0.999 | 0.00–Inf |
| Type 3 | 4.26 | 0.007 * | 1.47–12.32 | 1.31 | 0.705 | 0.33–5.25 |
| Surgical type | ||||||
| GTR | 1.00 | |||||
| Non-GTR | 7.86 | <0.001 * | 2.70–22.95 | 6.38 | 0.031 * | 1.18–34.37 |
Abbreviations: MRI, magnetic resonance imaging; IEDs, interictal epileptic discharges; GTR, gross total resection; Non-GTR, near-total resection and subtotal resection; HR, hazard ratio; CI, confidence intervals. * p < 0.05.