Treatment group was defined in a time-dependent fashion, at each 30-day interval. Type 2 and 4 angiotensin II receptor–stimulating antihypertensive medications were defined as angiotensin II receptor blockers, dihydropyridine calcium channel blockers, and/or thiazides. Type 2 and 4 angiotensin II receptor–inhibiting antihypertensive medications were defined as angiotensin-converting enzyme inhibitors, β-blockers, and/or nondihydropyridine calcium channel blockers. Mixed antihypertensive medications were defined as both type 2 and 4 angiotensin II receptor–stimulating and –inhibiting antihypertensive medications.