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. 2023 Jan 11;12(2):287. doi: 10.3390/cells12020287

Figure 1.

Figure 1

STO-609 and some reported (Price et al. numbering noted in parenthesis [47]) CAMKK2 inhibitors. Potencies are depicted as pIC50 values. pIC50 values are the negative log of the IC50 value (in molar). Thus, a pIC50 = 6 corresponds to an IC50 of 1μM, a pIC50 = 7 corresponds to an IC50 = 100 nM, a pIC50 = 8 corresponds to an IC50 = 10 nM, and a pIC50 = 9 corresponds to an IC50 = 1 nM.