Figure 4. Representative Comparison of Images for Patient C.

Comparison is shown between wide-field optical coherence tomography and permanent histology of invasive human papillomavirus–related squamous cell carcinoma exhibiting an exophytic papillary component. A, The superior margin of the right tonsil is shown, with wide-field optical coherence tomography in the top panel showing squamous cell carcinoma. In the bottom panel, a hematoxylin and eosin slide from the corresponding region is shown. B, The anterior margin is shown, with wide-field optical coherence tomography of the superior margin showing squamous epithelium (SE), lymph node (LN), and a crypt (C) in the top panel. In the bottom panel, a hematoxylin and eosin slide from the corresponding region is shown.