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. 2023 Jan 5;15(2):346. doi: 10.3390/cancers15020346

Table 5.

HT in patients with soft tissue sarcoma, bladder cancer and glioma. Summary of articles reviewed.

Author Article Type Investigation Total
Participants
Survival Outcome
Soft Tissue Sarcoma
Issels et al., 2018 [72] Phase III RCT HT + NACT vs. NACT alone in localised high-risk STS N = 341 Improved response.
Improved LPFS and DFS.
OS improved (HR = 0.73; p = 0.04).
Bladder Cancer
Van der Zee et al., 2000 [28] Phase III RCT HT + RT vs. RT alone in advanced pelvic tumours N = 101 (MIBC) Improved CR.
No difference in OS and LC rates.
Glioma
Mahdavi et al., 2020 [76] Prospective comparative trial CTRT vs. CTRT + HT in glioblastoma N = 38 Improved response.
No difference in OS or performance score change.