Table 5.
IDH status classification performances in adult-type gliomas (WHO CNS5).
| Classification Metrics | cMRI | Multi-Shell dMRI | cMRI and Multi-Shell dMRI |
|---|---|---|---|
| Overall performance | |||
| Accuracy | 74 ± 5% | 73 ± 6% | 81 ± 5% |
| Precision 1 | 0.77 ± 0.04 | 0.77 ± 0.09 | 0.83 ± 0.04 |
| MCC | 0.52 ± 0.08 | 0.52 ± 0.18 | 0.64 ± 0.06 |
| Individual group sensitivity | |||
| IDH mutant | 84 ± 6% | 84 ± 6% | 89 ± 8% |
| IDH wildtype | 64 ± 9% | 62 ± 6% | 73 ± 13% |
Classification performance of ResNet on the unseen test sets with different MRI inputs to diagnose IDH mutation status on the whole cohort of 146 patients with low- and high-grade gliomas. Data are reported as average ± standard deviation over the five test sets in the outer loop. 1 Computed as the macro-average of the precisions for the IDH-mutant group and the IDH-wildtype group. IDH = isocitrate dehydrogenase; cMRI = conventional MRI; dMRI = diffusion MRI; MCC = Matthews correlation coefficient.