Figure 3.

Combined raloxifene/paclitaxel treatment increases apoptosis in L3.6pl cells. TUNEL staining and subsequent FACS analysis were performed on L3.6pl cells treated with different concentrations of raloxifene (Ral), SC144 and paclitaxel (Pacli) alone or in combination. Staurosporine served as positive control, unstained cells served as negative control. The graphs show the mean values ± SEM of n = 4–5. * p < 0.05 and *** p < 0.001 versus control; ^# p < 0.05 and ^## p < 0.01 versus paclitaxel.