Table 2. Cox Proportional Hazard Model Coefficientsa.
Characteristic at index date | HR (95% CI) |
---|---|
Age, y | |
50-59 | 1 [Reference] |
60-69 | 0.97 (0.94-1.01) |
70-75 | 0.97 (0.93-1.01) |
Sex | |
Female | 1 [Reference] |
Male | 0.99 (0.96-1.02) |
Race | |
Asian | 0.79 (0.69-0.91) |
Black | 0.85 (0.80-0.91) |
White | 1 [Reference] |
Unknown | 0.93 (0.86-1.02) |
Ethnicity | |
Hispanic | 0.94 (0.84-1.04) |
Non-Hispanic | 1 [Reference] |
Unknown | 0.96 (0.88-1.04) |
Insurance type | |
Commercial | 1 [Reference] |
Medicaid | 0.79 (0.73-0.85) |
Medicare | 0.95 (0.91-0.99) |
Other | 0.87 (0.76-0.99) |
Unknown | 0.67 (0.58-0.77) |
Smoking status | |
Never smoked | 1 [Reference] |
Current smoker | 0.87 (0.84-0.91) |
Not currently smoking | 1.03 (0.97-1.10) |
Previously smoked | 0.97 (0.94-1.01) |
Prior SBT use | |
No | 1 [Reference] |
Yes | 1.12 (1.08-1.16) |
Index year | |
2017 | 1 [Reference] |
2018 | 1.00 (0.96-1.05) |
2019 | 0.90 (0.86-0.93) |
2020 | 0.72 (0.68-0.77) |
SBT type | |
FIT | 1 [Reference] |
mt-sDNA | 1.63 (1.57-1.68) |
CCI levels | |
0 | 1 [Reference] |
1-2 | 0.89 (0.87-0.92) |
3-4 | 0.72 (0.68-0.77) |
5+ | 0.64 (0.59-0.71) |
Abbreviations: CCI, Charlson Comorbidity Index; FIT, fecal immunochemical tests; HCO, health care organizations; HR, hazard ratio; mt-sDNA, multitarget stool DNA; SBT, stool-based test.
Model also included adjustment for HCO identity (coefficients in eTable 1 in Supplement 1).