. 2023 Jan 18;6(1):e2251360. doi: 10.1001/jamanetworkopen.2022.51360

Table 2. Multivariable Poisson Regression Models Reporting RRs of Longer-Term COVID-19 Symptoms Reported 28 or More Days or 90 or More Days After Symptom Onset.

Variable	≥28 d (n = 1807)		≥90 d (n = 1726)
Variable	RR (95% CI)	P value	RR (95% CI)	P value
Unvaccinated prior to infection	1.39 (1.04-1.85)	.02	1.37 (0.88-2.13)	.17
Delta variant period^a	0.92 (0.71-1.20)	.53	0.68 (0.46-1.02)	.07
Maximum symptom severity during acute illness
None or mild	1 [Reference]	NA	1 [Reference]	NA
Moderate	1.80 (1.47-2.22)	.00	2.19 (1.62-2.96)	.00
Severe or critical	2.25 (1.80-2.81)	.00	2.88 (2.09-3.97)	.00
Days hospitalized^b	1.02 (1.00-1.03)	.01	1.02 (1.00-1.03)	.03
Reported respiratory symptoms on enrollment form	1.14 (0.97-1.34)	.11	0.96 (0.76-1.20)	.70
Age group, y
18-44	1 [Reference]	NA	1 [Reference]	NA
45-64	1.02 (0.81-1.30)	.85	1.10 (0.79-1.53)	.57
≥65	0.93 (0.62-1.41)	.74	1.20 (0.68-2.12)	.53
Sex
Female	1.13 (0.97-1.31)	.11	1.20 (0.97-1.48)	.09
Male	1 [Reference]	NA	1 [Reference]	NA
Charlson Comorbidity Index score
0	1 [Reference]	NA	1 [Reference]	NA
1-2	1.07 (0.83-1.38)	.59	0.85 (0.59-1.21)	.37
3-4	1.02 (0.68-1.53)	.91	0.80 (0.45-1.41)	.44
≥5	1.55 (1.01-2.37)	.046	1.25 (0.69-2.26)	.46
BMI category^c
Underweight or normal weight	1 [Reference]	NA	1 [Reference]	NA
Overweight	1.03 (0.84-1.26)	.77	0.98 (0.74-1.29)	.87
Obesity	0.95 (0.76-1.19)	.64	0.90 (0.66-1.23)	.51
Severe obesity	1.04 (0.81-1.35)	.74	1.12 (0.79-1.59)	.51

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); NA, not applicable; RR, risk ratio.

^{^a}

July 1 to December 31, 2021.

^{^b}

The RRs reported are per day of hospitalization.

^{^c}

Underweight or normal weight was defined as less than 25; overweight, 25 to 29; obesity, 30 to 34; and severe obesity, 35 or higher.