Skip to main content
. 2023 Jan 14;12(2):317. doi: 10.3390/cells12020317

Table 2.

A selected panel of subunit antigens against Mtb.

Mtb Protein Putative Function Immunogenic
Function
Localisation Structural Information (pdb Code) Reference
Rv2450c (RpfE) Cell Wall Hydrolase -DC maturation periplasm 4CGE [119,120]
Rv1009 (RpfB) Cell Wall Hydrolase -DC maturation periplasm 4KL7, 4KPM, 4EMN, 3EO5, 5E27 [121,122,123,124]
Rv2882c Ribosome recycling factor -Macrophage-
activator
-Boosting BCG
cytoplasm 4KAW, 4KB2, 4KB4, 4KC6, 4KDD [125]
Rv2005c USP -DC maturation when fused to Rv2882c cytoplasm No structure available [126]
Rv3463 Oxidoreductase -Macrophage-
activator
cytoplasm No structure available [127]
Rv1876 Bacterioferritin -DC maturation
-Boosting BCG
cytoplasm 3UOF, 3QB9, 3UOI [128]
Rv2299c Mycobacterial
Chaperone
-DC maturation
-Boosting BCG fused with ESAT6
cytoplasm No structure available [129,130,131]