Table 2.
Mtb Protein | Putative Function | Immunogenic Function |
Localisation | Structural Information (pdb Code) | Reference |
---|---|---|---|---|---|
Rv2450c (RpfE) | Cell Wall Hydrolase | -DC maturation | periplasm | 4CGE | [119,120] |
Rv1009 (RpfB) | Cell Wall Hydrolase | -DC maturation | periplasm | 4KL7, 4KPM, 4EMN, 3EO5, 5E27 | [121,122,123,124] |
Rv2882c | Ribosome recycling factor | -Macrophage- activator -Boosting BCG |
cytoplasm | 4KAW, 4KB2, 4KB4, 4KC6, 4KDD | [125] |
Rv2005c | USP | -DC maturation when fused to Rv2882c | cytoplasm | No structure available | [126] |
Rv3463 | Oxidoreductase | -Macrophage- activator |
cytoplasm | No structure available | [127] |
Rv1876 | Bacterioferritin | -DC maturation -Boosting BCG |
cytoplasm | 3UOF, 3QB9, 3UOI | [128] |
Rv2299c | Mycobacterial Chaperone |
-DC maturation -Boosting BCG fused with ESAT6 |
cytoplasm | No structure available | [129,130,131] |