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. 2023 Jan 13;6(1):e2250921. doi: 10.1001/jamanetworkopen.2022.50921

Table 2. Variables Facilitating a Safer Disclosure in Individuals With SCD+ and Amyloid-Positive Results.

Features IES-R Changes in HADS
Total Avoidance Intrusions Hyperarousal Anxiety Depression
Index, W P value Index, W P value Index, W P value Index, W P value Index, W P value Index, W P value
Age (y), ρ –0.15 .45 –0.16 .44 –0.19 .35 0.07 .73 –0.02 .91 –0.25 .23
Gender 92.0 .98 91.5 1.00 102.0 .61 70.5 .32 85.5 .98 106.5 .26
Education (years), ρ –0.18 .37 –0.13 .51 –0.07 .73 –0.43 .02 –0.15 .48 –0.15 .46
MMSE, ρ 0.21 .29 0.35 .07 –0.01 .95 0.04 .83 0.23 .26 –0.10 .61
Communication that SCD+ is a risk condition 1.5 .16 6.5 .41 2.0 .17 3.5 .24 14.0 .89 18.0 .50
Disclosure type
(face to face vs phone)
72.0 .30 64.5 .54 68.5 .41 65.0 .55 51.0 .64 27.0 .23
Disclosure duration (min), ρ 0.02 .93 0.16 .44 0.03 .90 –0.31 .13 –0.28 .18 –0.27 .19
Presence of study partner 7.5 .03 21.0 .23 11.5 .06 15.0 .11 49.0 .26 24.0 .41

Abbreviations: HADS, Hospital Anxiety and Depression scale; IES-R, Impact of Events Scale–Revised; MMSE, Mini Mental State Examination; SCD+, subjective cognitive decline plus.