TABLE 4.
Housekeeping alleles shared by GAS and GCS-GGSa
| Locus | Shared GCS-GGS allele | GCS-GGS emm types represented | Group carbohydrate represented | No. of GCS-GGS isolates represented | GCS-GGS allelic frequency | Shared GAS allele | GAS emm types represented | No. of GAS isolates represented | GAS allelic frequency |
|---|---|---|---|---|---|---|---|---|---|
| gtr | 101 | stG4974, stG480 | G | 2 | 0.0588 | 03 | 1, 87, st4935 | 18 | 0.0849 |
| 102 | stC839, stG4831 | C, G | 2 | 0.0588 | 06 | 3, 28, 49, 53, 60, 76, 77, 91, st4973, st64/14, stD633, stNS5 | 40 | 0.1887 | |
| 103 | stG480 | G | 1 | 0.0294 | 13 | 93 | 1 | 0.0047 | |
| 104 | stC839, stG11 | C, G | 3 | 0.0882 | 26 | 57 | 1 | 0.0047 | |
| murI | 101 | stG480 | G | 1 | 0.0294 | 04 | 1 | 22 | 0.1038 |
| 102 | stG480 | G | 1 | 0.0294 | 08 | 3, 4, 8, 19, 24, 26, 29, 34, 52, 66, 78, 89, 93, st1RP31, st2370.1, st4973, st64/14 | 55 | 0.2594 | |
| 103 | stG4831 | G | 1 | 0.0294 | 24 | 70 | 1 | 0.0047 | |
| 104 | stG643 | G | 1 | 0.0294 | 02 | 12, 14, 39, 49, 51, 55, 63, 77, 81, 83, 90, 91, st3365, st4529, st4935, st833, stD432, stD633 | 30 | 0.1415 | |
| mutS | 101 | stG643 | G | 1 | 0.0294 | 07 | 9, 11, 25, 42, 49, 57, 60, 81, 89, stD432 | 14 | 0.0660 |
| recP | 105 | stG10 | G | 1 | 0.0294 | 02 | 2, 3, 33, 43, 53, 83, 90, 91, 92, 93, st2370.1, st4935, st4973, stNS5 | 46 | 0.2170 |
| 106 | stG4974 | G | 1 | 0.0294 | 04 | 1, 70, st4529 | 22 | 0.1038 | |
| xpt | 103 | stG643 | C | 1 | 0.0294 | 02 | 1, 4, 12, 33, 42, 52, 53, 60, 76, 87, 91, 92, stNS5 | 55 | 0.2594 |
| yqiL | 101 | stG4974 | G | 1 | 0.0294 | 12 | 51, st2370.1, st3365 | 3 | 0.0142 |
| 102 | stG480 | G | 1 | 0.0294 | 04 | 1, 2, 4, 8, 11, 22, 25, 49, 50, 62, 68, 73, 76, 44/61, 90, st833 | 43 | 0.2029 | |
| 103 | stG480 | G | 1 | 0.0294 | 15 | 88, 92 | 3 | 0.0142 | |
| 105 | stC839 | C | 1 | 0.0294 | 01 | 1, 4, 9, 11, 13, 32, 39, 49, 66, 67, 78, 44/61, 82, 89, st2346, st4592, st4935, st64/14 | 48 | 0.2264 |
Analysis includes 34 isolates of GCS and GGS (S. dysgalactiae subsp. equisimilis) and 212 isolates of GAS. Minimum possible allelic frequencies are 0.0294 and 0.0047 for GCS-GGS and GAS, respectively.