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. 2022 Dec 8;9(2):215–224. doi: 10.1001/jamaoncol.2022.5816

Figure 5. One-Stage Pooled Analysis of First-line Combined Positive Score (CPS) Studies (ORIENT-15 and KEYNOTE-590).

Figure 5.

A, There was a significant difference in overall survival for the overall group comparing immunochemotherapy (hazard ratio [HR], 0.67; 95% CI, 0.58-0.78; P < .001) with chemotherapy alone. B, There was a significant difference in overall survival for the group with a CPS of 10 or higher comparing immunochemotherapy (HR, 0.60; 95% CI, 0.49-0.73; P < .001) with chemotherapy alone. C, There was a significant difference in overall survival for the subgroup with a CPS lower than 10 comparing immunochemotherapy with chemotherapy alone (HR, 0.77; 95% CI, 0.62-0.94; P = .01).