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. 2023 Jan 3:e225090. Online ahead of print. doi: 10.1001/jamapediatrics.2022.5090

Table 3. Secondary Analyses.

Moderator K Hedges g (95% CI) I2, % P valuea
Moderator Contrast
Sex
Both males and females 18 −0.19 (−0.35 to −0.04) 49 .01 .03
Female 3 −0.90 (−2.26 to 0.45) 64 .10
Age, y
<13 8 −0.05 (−0.18 to 0.09) 6 .44 .002
≥13 13 −0.44 (−70 to −0.19) 62 .003
Health status
Healthy 9 −0.09 (−0.18 to −0.00) 0 .05 <.001
Physical illness 6 −0.22 (−0.71 to 0.28) 74 .31
Mental illness 6 −0.74 (−1.01 to −0.47) 0 <.001
Depression diagnosis
Yes 5 −0.75 (−1.09 to −0.41) 0 .004 <.001
No 16 −0.13 (−0.28 to 0.01) 41 .07
Monotherapy
Yes 17 −0.33 (−0.55 to −0.11) 63 .006 .39
No 4 −0.16 (−0.68 to 0.35) 71 .38
Supervision
Fully supervised 16 −0.17 (−0.33 to −0.02) 44 .03 <.001
Partially supervised 3 −0.20 (−1.01 to 0.61) 44 .40
Not supervised 2 −1.06 (−1.95 to −0.18) 0 .04
Control
Usual care 7 −0.11 (−0.38 to 0.16) 59 .34 .11
No intervention 9 −0.50 (−0.87 to −0.13) 67 .01
Attention 4 −0.13 (−0.54 to 0.28) 7 .38
Waiting list 1 −0.34 (−0.91 to 0.23) NA .25
Study design
RCT 17 −0.25 (−0.43 to −0.06) 37 .01 .56
NRCT 4 −0.42 (−1.31 to 0.47) 81 .23
Intention to treat
Yes 6 −0.15 (−0.30 to 0.01) 0 .06 .12
No 15 −0.36 (−0.62 to −0.10) 72 .01
Frequency, d/wk
2 5 −0.06 (−0.25 to 0.12) 5 .39 .03
3 8 −0.57 (−1.00 to −0.14) 74 .02
≥4 8 −0.19 (−0.43 to 0.04) 51 .09
Session, min
<45 10 −0.27 (−0.54 to −0.01) 49 .04 .83
≥45 11 −0.31 (−0.61 to −0.01) 72 .04
Duration, wk
<12 9 −0.58 (−0.96 to −0.20) 59 .008 .01
≥12 12 −0.12 (−0.27 to 0.02) 37 .08
Intensity
Low to moderate 7 −0.41 (−0.89 to 0.08) 67 .09 .65
Vigorous 10 −0.13 (−0.31 to 0.04) 41 .11
Not reported 4 −0.53 (−1.32 to 0.25) 75 .12

Abbreviations: NA, not applicable; NRCT, nonrandomized clinical trial; RCT, randomized clinical trial.

a

The moderator P value indicates the P value for the pooled estimate effect of the subgroup defined by the level of the moderator; the contrast P value indicates the P value of the effect of the moderator in the corresponding meta-regression.