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. 2023 Jan 12;9(3):414–418. doi: 10.1001/jamaoncol.2022.6303

Table. Adjusted Changes in Serious Illness Conversations and End-of-Life Outcomes.

No./total No. (%) of encounters Odds of an SIC, aOR (95% CI)a P value
Control period Intervention period
SICs
All patient encounters 158/12 356 (1.3) 1262/28 665 (4.4) 2.09 (1.53-2.87) <.001
Encounters with high-risk patientsb 59/1754 (3.4) 510/3765 (13.5) 2.62 (1.84-3.72) <.001
Encounters with non–high-risk patients 99/10 602 (0.9) 752/24 899 (3.0) 2.07 (1.52-2.82) <.001
Deceased patients 42/215 (19.5) 377/1202 (31.4) 2.44 (1.35-4.42) <.001
End-of-life outcomes
All patients
Inpatient deathc 27/231 (11.7) 114/957 (11.9) 1.72 (0.7-4.24) .24
ICU admission within 30 d of deathc 39/231 (16.9) 150/957 (15.7) 1.04 (0.54-1.98) .92
Enrolled in hospicec 93/156 (59.6) 424/700 (60.6) 1.42 (0.78-2.59) .25
Hospice length of stay, mean (SD), dd 23.90 (40.77) 25.53 (37.01) 1.26 (0.67-2.37) .47
Systemic therapy within 14 d of deathc 24/231 (10.4) 72/957 (7.5) 0.25 (0.11-0.57) .001
High-risk patients
Inpatient death 22/181 (12.2) 83/696 (11.9) 1.8 (0.63-5.13) .27
ICU admission within 30 d of death 28/181 (15.5) 120/696 (17.2) 1.12 (0.51-2.45) .77
Enrolled in hospicec 79/124 (63.7) 340/525 (64.8) 1.53 (0.72-3.25) .27
Hospice length of stay, mean (SD), dd 26.33 (43.53) 25.03 (36.65) 1.24 (0.64-2.41) .53
Systemic therapy within 14 d of deathc 15/181 (8.3) 50/696 (7.2) 0.37 (0.13-1.04) .06
Non–high-risk patients
Inpatient death 5/50 (10) 31/261 (11.9) 1.03 (0.62-1.69) .92
ICU admission within 30 d of death 11/50 (22) 30/261 (11.5) 0.96 (0.63-1.47) .87
Enrolled in hospicec 14/32 (43.8) 84/175 (48) 1.31 (0.96-1.79) .08
Hospice length of stay, mean (SD), dd 25.03 (33.46) 26.39 (35.46) 0.68 (0.18-2.56) .57
Systemic therapy within 14 d of death 9/70 (12.90) 22/347 (6.30) 0.84 (0.44-1.61) .61

Abbreviations: aOR, adjusted odds ratio; ICU, intensive care unit; SIC, serious illness conversation.

a

Adjusted for intervention, clinic group, and wedge, and clustered at the oncologist level.

b

High-risk patients were defined as having a 10% or greater risk of death within 180 days, as identified by a prospectively validated machine learning algorithm.

c

End-of-life inpatient and systemic therapy data available for 1188 patients.

d

Hospice outcomes available for 856 patients who were eligible for health system–affiliated hospice.