Table 5.
Dependency between stage of the disease and EMVI (broken down into groups by the level of LMR, NLR and PLR).
| Stage, n (%) | EMVI − | EMVI + | p |
|---|---|---|---|
| LMR ≤ median | |||
| II–III A | 29 (58.0) | 15 (38.5) | 0.002 |
| III B | 19 (38.0) | 11 (28.2) | |
| III C | 2 (4.0) | 13 (33.3) | |
| LMR > median | |||
| II–III A | 30 (57.7) | 10 (27.0) | 0.002 |
| III B | 19 (36.5) | 16 (43.2) | |
| III C | 3 (5.8) | 11 (29.7) | |
| NLR ≤ median | |||
| II–III A | 30 (55.6) | 12 (34.3) | 0.008 |
| III B | 21 (38.9) | 13 (37.1) | |
| III C | 3 (5.6) | 10 (28.6) | |
| NLR > median | |||
| II–III A | 29 (60.4) | 13 (31.7) | 0.001 |
| III B | 17 (35.4) | 14 (34.1) | |
| III C | 2 (4.2) | 14 (34.1) | |
| PLR ≤ median | |||
| II–III A | 31 (56.4) | 10 (29.4) | 0.010 |
| III B | 21 (38.2) | 16 (47.1) | |
| III C | 3 (5.5) | 8 (23.5) | |
| PLR > median | |||
| II–III A | 28 (59.6) | 15 (35.7) | <0.001 |
| III B | 17 (36.2) | 11 (26.2) | |
| III C | 2 (4.3) | 16 (38.1) | |
Bold font indicates statistical significance. EMVI, extramural vascular invasion; LMR, lymphocyte-to-monocyte ratio; NLR, neutrophil-to-monocyte ratio; PLR, platelet-to-lymphocyte ratio. Data presented as n (% of EMVI−/ EMVI + group). Dependencies were analysed with chi-square test.