Table 4.

Summarized diagnostic value of NBI for OPMD and OSCC within various subgroups.

Subgroup analysis	Studies	Participants	Sensitivity	Specificity	Diagnostic Odds Ratio	Positive likelihood ratio	Negative likelihood ratio	Area Under Curve
Subgroup 1	9	1179	0.87 (0.67, 0.96)	0.83 (0.56, 0.95)	87.40 (8.62, 886.50)	7.32 (1.60, 33.47)	0.08 (0.02, 0.29)	0.92 (0.89, 0.94)
Subgroup 2	9	1232	0.58 (0.19, 0.89)	0.95 (0.85, 0.99)	28.38 (7.18, 112.11)	12.42 (4.72, 32.68)	0.44 (0.16, 1.18)	0.94 (0.91, 0.96)
Subgroup 3	6	946	0.69 (0.47, 0.85)	0.97 (0.88, 0.99)	63.54 (20.17, 200.19)	20.14 (6.25, 64.85)	0.32 (0.17, 0.60)	0.93 (0.90, 0.95)
Subgroup 4	5	890	0.97 (0.82, 0.99)	0.55 (0.23, 0.83)	36.21 (5.38, 243.74)	2.14 (1.02, 4.49)	0.06 (0.01, 0.33)	0.92 (0.90, 0.94)

NBI, narrow band imaging; OSCC, oral squamous cell carcinoma; OPMD, oral potentially malignant disorders.