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. 2023 Jan 20;19(4):232–248. doi: 10.1038/s41574-022-00797-x

Fig. 4. Diabetes mellitus complication problems that might be solved with organoids.

Fig. 4

Examples of complications that can be studied with organoids. Organoid systems for different organs are at different stages of development, the pancreas, kidney and retina being the more advanced and organoids recapitulating nerves the least advanced. The disease-relevant assays that are already available (current in vitro systems) are summarized and interesting assays that might become testable (future developments) pending improvements of models are proposed.