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. 2023 Jan 20;18(1):e0267516. doi: 10.1371/journal.pone.0267516

Table 5. Between-reader agreement for the semi-quantitative tests.

Index test Kappa (simple) [95%CI] Kappa (weighted*) [95%CI] Concordant (n/N) [95%CI] Discordant (n/N) [95%CI]
BTNX Tri Line 0.831 [0.778, 0.884] 0.880 [0.843, 0.917] 88.3% (249/282) [84.0%, 91.8%] 11.7% (33/282) [8.2%, 16.0%]
ALLTEST Dipstick 0.818 [0.764, 0.873] 0.907 [0.877, 0.937] 88.0% (263/299) [83.7%, 91.4%] 12.0% (36/299) [8.6%, 16.3%]
BTNX Quad Line 0.811 [0.758, 0.863] 0.889 [0.856, 0.921] 86.0% (258/300) [81.6%, 89.7%] 14.0% (42/300) [10.3%, 18.4%]
BIOTEST 0.752 [0.693, 0.810] 0.868 [0.835, 0.901] 82.0% (246/300) [77.2%, 86.2%] 18.0% (54/300) [13.8%, 22.8%]
ALLTEST Cassette (four categories) 0.734 [0.673, 0.796] 0.861 [0.825, 0.896] 82.3% (247/300) [77.5%, 86.5%] 17.7% (53/300) [13.5%, 22. 5%]
NADAL Cassette 0.729 [0.669, 0.789] 0.835 [0.796, 0.873] 79.7% (239/300) [74.7%, 84.1%] 20.3% (61/300) [15.9%, 25.3%]
ACTIM CRP 0.725 [0.663, 0.787] 0.848 [0.811, 0.885] 81.7% (245/300) [76.8%, 85.9%] 18.3% (55/300) [14.1%, 23.2%]
NADAL Dipstick 0.674 [0.609, 0.739] 0.817 [0.779, 0.856] 77.3% (232/300) [72.2%, 81.9%] 22.7% (68/300) [18.1%, 27.8%]
ALLTEST Cassette (three categories) 0.599 [0.516, 0.682] 0.650 [0.575, 0.724] 76.8% (228/297) [71.5%, 81.5%] 23.2% (69/297) [18.5%, 28.5%]

Simple kappa, linear weighted kappa, and the percentages of concordant and discordant results are shown, including the 95% CI. The tests are ranked according to the simple kappa results. For each test, 300 measurements (100 samples in triplicate) were evaluated, except for the ALLTEST dipstick (1 of 300 was not evaluable) and the ALLTEST cassette (3 of 300 were not evaluable).