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. 2023 Jan 4;13(2):176. doi: 10.3390/diagnostics13020176

Table 2.

Patients’ colposcopic features summary statistics a by VAIN grade at diagnosis.

Characteristic Category VAIN Grade
All Patients
n = 255
VAIN 1
n = 52
VAIN 2
n = 55
VAIN 3 b
n = 148
p-Value
Grade G1 134 (53.4) 45 (88.2) 41 (74.6) 48 (33.1)
G2 117 (46.6) 6 (11.8) 14 (25.4) 97 (66.9) <0.001
Lesion type Flat 145 (59.2) 41 (80.4) 38 (70.4) 66 (47.1)
Papillary 100 (40.8) 10 (19.6) 16 (29.6) 74 (52.9) <0.001
Multifocality Unifocal 141 (56.6) 34 (65.4) 29 (53.7) 78 (54.6)
Multifocal 108 (43.4) 18 (34.6) 25 (46.3) 65 (45.4) 0.36
Vascular pattern No 196 (80.3) 51 (98.1) 51 (92.7) 94 (68.6)
Yes 48 (19.7) 1 (1.9) 4 (7.3) 43 (31.4) <0.001
Vaginal localization Vault 98 (38.7) 15 (28.9) 21 (38.2) 62 (42.5)
Upper third 114 (45.1) 24 (46.2) 24 (43.6) 66 (45.2)
Middle third 26 (10.3) 10 (19.2) 8 (14.6) 8 (5.5)
Lower third 15 (5.9) 3 (5.8) 2 (3.6) 10 (6.9) 0.09

an (column %); b Including n = 10 VAIN3 with stromal microinvasion; VAIN = Vaginal Intraepithelial Neoplasia; G = Grade.