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. 2023 Jan 4;13(2):176. doi: 10.3390/diagnostics13020176

Table 3.

Patients’ colposcopic features summary statistics a by VAIN grade at diagnosis, considering microinvasive VAIN3 as a separate category.

Characteristic Category VAIN
All Patients
n = 255
VAIN 1
n = 52
VAIN 2
n = 55
VAIN 3
n = 138
VAIN 3 Microinvasive
n = 10
p-Value
Grade G1 134 (53.4) 45 (88.2) 41 (74.6) 48 (35.6) 0
G2 117 (46.6) 6 (11.8) 14 (25.4) 87 (64.4) 10 (100) <0.001
Lesion type Flat 145 (59.2) 41 (80.4) 38 (70.4) 66 (50.4) 0
Papillary 100 (40.8) 10 (19.6) 16 (29.6) 65 (49.6) 9 (90.0) <0.001
Multifocality Unifocal 141 (56.6) 34 (65.4) 29 (53.7) 76 (56.7) 2 (22.2)
Multifocal 108 (43.4) 18 (34.6) 25 (46.3) 58 (43.3) 7 (77.8) 0.11
Vascularity No 196 (80.3) 51 (98.1) 51 (92.7) 89 (69.5) 5 (55.6)
Yes 48 (19.7) 1 (1.9) 4 (7.3) 39 (30.5) 4 (44.4) <0.001
Vaginal localization Vault 98 (38.7) 15 (28.9) 21 (38.2) 58 (42.7) 4 (40.0)
Upper third 114 (45.1) 24 (46.2) 24 (43.6) 61 (44.9) 5 (50.0)
Middle third 26 (10.3) 10 (19.2) 8 (14.6) 8 (5.9) 0
Lower third 15 (5.9) 3 (5.8) 2 (3.6) 9 (6.6) 1 (10.0) 0.23

an (column %); VAIN = Vaginal Intraepithelial Neoplasia; G = Grade.