Fig 4. Correlation of VEGF-A levels with other protein concentrations.

A) A significant correlation of Angiopoietin-1 and VEGF-A was noted for all samples (r = 0.228; p = 0.023; r² = 0.052). B) Scatterplot of Angiopoietin-2 versus VEGF-A. A significant correlation between Angiopoietin-2 level and VEGF-A could be observed (r = 0.348; p<0.001; r² = 0.121). C) Correlation analysis of VEGF-A and PIGF concentration also showed a significant correlation (r = 0.479; p < .001; r² = 0.229). D) Also, between Galectin-1 and VEGF-A a significant correlation was detectable (r = 0.271; p = 0.019; r² = 0.074). E) A significant correlation between IL-8 and VEGF-A was detectable (r = 0.371; p<0.001; r² = 0.138). F) In contrast, a correlation between levels of IL-1β and VEGF-A could not be observed (r = 0.196; p = 0.051; r² = 0.039). Each blue dot represents one patient, linear regressions are displayed as solid grey lines.