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. 2023 Jan 20;18(1):e0273136. doi: 10.1371/journal.pone.0273136

Fig 3. Examples of the topologies observed in the PolyDIV AlphaFold models.

Fig 3

Colored from N-terminus (blue) to C-terminus (red). (A) The PURPLE_3_monomer model shows its DivIVA-like domains interacting in a consecutive manner, first with second and third with fourth. (B) The PURPLE_3+DivIVA_monomer shows a non-consecutive DivIVA-like topology. (C) PURPLE_3_dimer shows a topology equivalent to that of (A), where the two chains do not interact via their DivIVA-like domains. (D) PURPLE_1_dimer shows a complex topology where one or more DivIVA-like domains interact with another DivIVA-like domain from another polypeptide chain. All sequences and models are provided in the S1 File.