Table 3.

Distribution (median and interquartile range) of DNA methylation of 10 genes among 62 trauma-exposed women and 50 trauma-free controls.

	Exposed (n = 62)			Non Exposed (n = 50)
	I Quartile	Median	III Quartile	I Quartile	Median	III Quartile	p-Value *
ADCYAP1	0.11	0.13	0.15	0.11	0.13	0.16	0.307
BDNF	0.07	0.08	0.10	0.06	0.07	0.08	0.002
CRHR1	0.07	0.08	0.08	0.07	0.08	0.08	0.496
DRD2	0.10	0.14	0.17	0.08	0.11	0.14	0.003
FKBP5	0.04	0.05	0.05	0.05	0.05	0.06	0.018
IGF2	0.49	0.53	0.56	0.45	0.48	0.52	0.001
LSD1	0.04	0.04	0.05	0.03	0.04	0.06	0.186
NR3C1	0.03	0.04	0.05	0.03	0.04	0.05	0.188
PRTFDC1	0.03	0.04	0.05	0.04	0.04	0.05	0.271
SLC6A4	0.04	0.05	0.05	0.04	0.05	0.05	0.347

* Non-parametric Wilcoxon rank-sum test (since Bonferroni’s correction for multiple comparisons is adopted, a p-value < 0.005 (0.05/10) indicates that the median is statistically different between groups). BDNF, DRD2, and IGF2 resulted in hypermethylated in trauma-exposed women.