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. 2022 Dec 30;14(1):113. doi: 10.3390/genes14010113

Table 3.

Genetic diversity analysis of PRKAA2 mutant groups.

SNPs Genotypic Frequencies Allelic
Frequency
He Ho Ne PIC χ2
g.42101G>T GG GT TT G T 0.498 0.502 1.991 0.374 1.833
0.244 (40) 0.445 (73) 0.311 (51) 0.466 0.534
g.60146A>T AA AT TT A T 0.480 0.520 1.922 0.365 2.482
0.390 (64) 0.421 (69) 0.189 (31) 0.601 0.399
g.61455G>A GG GA AA G A 0.499 0.501 1.996 0.375 0.649
0.213 (35) 0.530 (87) 0.256 (42) 0.479 0.521

Note: HE, heterogeneity; HO, pureness; NE, effective allele; PIC, polymorphic information content; PIC < 0.25 implies low polymorphism; 0.5 > PIC > 0.25 denotes moderate polymorphism; PIC > 0.5 suggests high polymorphism; χ2 < 5.99 denotes Hardy-Weinberg equilibrium; χ2 > 5.99 signifies Hardy-Weinberg disequilibrium.