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. 2023 Jan 3;14(1):131. doi: 10.3390/genes14010131

Table 1.

Summary of the proposed mechanism of non-coding RNAs in leukemia.

Type Effector Target Reference(s)
miRNA miR-194-5p BCLAF1 [21]
miR-628 IGF-1R [22]
miR-143 Autophagy [23]
miR-126 SHIP1 and CEBPB [24,25]
miR-133 Evi1 [26]
miR-223 G1/S cell cycle [27,28,29]
miR-181a Cell proliferation and enhanced cell cycling [30]
miR-128 Apoptosis, genome instability, and drug sensitivity [31]
miR-125b Cell survival and lowered apoptosis [32]
miR-222 ETS1 [33]
miR-223 FOXO1 [34]
miR-142-3p Drug resistance [35]
miR-26b PIK3CD [36]
miR-26 Ikaros [37]
miR-30a NOTCH1 and NOTCH2 [38]
miR-221 STAT5 [39]
miR-497 CDKN2A/B [40]
miR-328 MALAT1 [41]
miR-214 ABCB1 [42]
miR-10a USF1 [43]
miR-203 Proliferation [44]
miR-29b Abl-1 [45]
miR-320 ABL [46]
miR -181a and miR-181b Drug resistance [47,48]
miR-125b GRK2 and PUMA [49]
lncRNA RP11-137H2.4 NR3C1 [50]
CRNDE Proliferation [51]
PVT1 Myc [52]
TUG1 Proliferation [53]
CCAT1 Proliferation and myeloid cell differentiation [54]
NR-104098 EZH2 [55]
LINC00265 PI3K-Akt [56]
NEAT1 Proliferation and drug resistance [57]
HOTAIR MRP1 [58,59]
SGNH5 Drug resistance [60]
Hmrhl Tumor development [61]
circRNA Circ-DLEU2 proliferation [62]
Circ_0004277 miR-134-5p and SSBP2 [63]
CircSPI1 SPI1 [64]
CircMYBL2 FLT3 [65,66,67]
Circ _004136 miR-142 and miR-29a [68]
CircRNF13 miR-1224-5p [69]
Circ_0121582 miR-224 [70]
Circ_100290 miR-203 [71]
Circ_0079480 miR-655-3p [72]
Circ_0002483 Cell proliferation and cell cycle arrest [73]
CircBA1 Cell growth and medication resistance [74]
CircCRKL miR-877-5p [75]
Circ-0058493 miR-548b-3p [76]
Circ-0132266 miR-337-3p [77]
CircZNF91 miR-1283 [78]
HOXB-AS3 Ribosomal RNA transcription [79]
piRNA and snoRNA 11186 CDKN2B [80]
823 DNA methylation and angiogenesis [81]
SNORD42A Proliferation [82]
SNHG12 miR-195 [83]