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. 2023 Jan 8;14(1):172. doi: 10.3390/genes14010172

Figure 1.

Figure 1

Characteristics of the mouse Phf8 and Phf8-ps genes. (A) Schematic depicting the chromosomic location of Phf8 and Phf8-ps genes in the mouse genome, and the respective transcripts produced by these genes. Exons are represented in blue boxes (excepted alternative exon 13 in beige) and introns by a line (image created with Biorender.com). (B) Schematic diagram of PHF8 protein structure with the functional PHD and JmjC domains. (C) Alignment of protein sequences of PHF8-PS and PHF8 isoforms. Sequences were obtained from the NCBI Ref seq database. Sequence alignments were performed using Jalview (version 2.11.2.3) and the Clustal Omega algorithm with default parameters. The conserved PHD and JmjC domains are respectively underlined in green and orange.