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. Author manuscript; available in PMC: 2023 Jan 20.
Published in final edited form as: J Neural Transm (Vienna). 2022 Oct 28;129(12):1487–1511. doi: 10.1007/s00702-022-02550-0

Table 7.

Average AUC (in bold), sensitivity, and specificity based on the five cross-validation folds of the univariate (i.e., only including individual features) and multivariate (i.e., including all features) LDAs for the clinical groups as a whole and for each group individually.

ALS PA PD nfPPA+PAOS Average AUC for All Clinical Groups Comparison of Average AUCs for All Clinical Groups
Coord .69, .62, .79 .57, .67, .58 .70, .74, .69 .88, .88, .85 .71 Coord-All Features p < .05*

Con .55, .66, .55 .75, .76, .74 .74, .79, .66 .39, .53, .52 .61 Con-All Features p < .001***
Speed .36, .41, .51 .53, .66, .50 .54, .60, .63 .63, .80, .58 .52 Speed-All Features p < .001***
Prec .56, .73, .51 .43, .39, .67 .63, .67, .64 .69, .73, .69 .58 Prec-All Features p < .001***
Rate .45, .54, .54 .67, .69, .66 .74, .79, .66 .91, .93, .85 .69 Rate-All Features p < .05*
All Features .64, .64, .66 .80, .75, .82 .83, .82, .78 .95, .88, .96 .81

Note. ALS = amyotrophic lateral sclerosis; PA = progressive ataxia; PD = Parkinson’s disease; nfPPA+PAOS = the nonfluent variant of primary progressive aphasia and progressive apraxia of speech.