Table 2:
Questionnaire Responses by OAB sub group
| p-value * = significant with FDR correction | |||||||
|---|---|---|---|---|---|---|---|
| Questionnaire | Question | Scale | Control (Mean) |
Dry (Mean) |
Wet (Mean) |
dry vs. control | dry vs. wet |
| LUTS 1 | How often during the past week did you urinate too frequently? | 0–4 | 0.23 | 2.57 | 2.52 | <0.001* | 0.942 |
| LUTS 2 | During a typical day in the past week, how many times did you urinate during waking hours? | 0–4 | 0.80 | 2.00 | 1.64 | <0.001* | 0.030 |
| LUTS 3 | During a typical night in the past week, how many times did you wake up because you needed to urinate? | 0–4 | 0.55 | 1.83 | 1.74 | <0.001* | 0.008* |
| LUTS 4 | During the past week, how often have you had the feeling your bladder was not empty after urinating? | 0–4 | 0.06 | 1.50 | 1.24 | <0.001* | <0.001* |
| LUTS 6 | During the past week, how often have you had a sudden need to rush to urinate? | 0–4 | 0.35 | 2.34 | 2.56 | <0.001* | 0.022 |
| LUTS 7 | During the past week, how often have you had a delay before you start to urinate? | 0–4 | 0.08 | 0.71 | 0.57 | <0.001* | 0.684 |
| LUTS 9 | During the past week, how often did you strain to urinate or strain while you were urinating? | 0–4 | 0.03 | 0.71 | 0.33 | <0.001* | 0.025 |
| LUTS 12 | During the past week, how often have you had a sudden need to rush to urinate for fear of leaking urine? | 0–4 | 0.24 | 1.55 | 2.52 | <0.001* | <0.001* |
| LUTS 13 | During the past week, how often have you had pain or discomfort in your bladder area? | 0–4 | 0.03 | 0.88 | 0.55 | <0.001* | <0.001* |
| LUTS 14 | During the past week, how often have you had a burning feeling when you urinate? | 0–4 | 0.02 | 0.27 | 0.12 | 0.005* | 0.154 |
| LUTS 15 | During the past week, how often did you leak urine? | 0–4 | 0.24 | 0.66 | 2.05 | 0.001* | <0.001* |
| LUTS16a | Leaked urine in connection with a sudden need to rush to urinate? | 0–4 | 0.15 | 0.40 | 2.59 | 0.003* | <0.001* |
| LUTS 16e | Leaked urine when you are sleeping? | 0–4 | 0.00 | 0.12 | 0.64 | 0.035* | 0.001* |
| AUA-SI 5 | Over the past month or so, how often have you found it difficult to postpone urination? | 0–5 | 0.14 | 2.70 | 3.37 | <0.001* | 0.031 |
| AUA-SI 6 | Over the past month or so, how often have you had a weak urine stream? | 0–5 | 0.06 | 1.27 | 0.94 | <0.001* | 0.310 |
| AUA-SI 7 | Over the last month or so, how often have you had to push or strain to begin urination? | 0–5 | 0.00 | 0.85 | 0.30 | <0.001* | 0.003* |
| AUA-SI 8 | If you were to spend the rest of your life with your urinary condition just the way it is now, how would you feel about that? | 0–6 | 0.56 | 4.05 | 4.33 | <0.001* | 0.197 |
| fGUPI1a | Pain/discomfort at the entrance to the vagina | 0–1 | 0.00 | 0.22 | 0.14 | 0.699 | 0.911 |
| fGUPI1b | Pain/discomfort in the vagina | 0–1 | 0.00 | 0.20 | 0.09 | 0.713 | 0.862 |
| fGUPI1c | Pain/discomfort in the urethra | 0–1 | 0.00 | 0.13 | 0.06 | 0.767 | 0.891 |
| fGUPI1d | Pain/discomfort below the waist, in pubic or bladder area | 0–1 | 0.00 | 0.34 | 0.21 | 0.631 | 0.883 |
| fGUPI2a | Pain or burning during urination | 0–1 | 0.00 | 0.08 | 0.05 | 0.816 | 0.945 |
| fGUPI2b | Pain or discomfort during or after sexual intercourse | 0–1 | 0.00 | 0.11 | 0.11 | 0.785 | 1.000 |
| fGUPI2c | Pain or discomfort as your bladder fills | 0–1 | 0.00 | 0.34 | 0.22 | 0.632 | 0.893 |
| fGUPI2d | Pain or discomfort relieved by voiding | 0–1 | 0.00 | 0.45 | 0.21 | 0.580 | 0.801 |
| fGUPI3 | Frequency of pain or discomfort over the last week | 0–5 | 0.03 | 1.12 | 0.93 | <0.001* | 0.072 |
| fGUPI4 | Number that best describes average pain/discomfort | 0–10 | 0.10 | 2.08 | 1.56 | <0.001* | 0.059 |
| fGUPI5 | Frequency of sensation of incomplete emptying | 0–5 | 0.02 | 1.41 | 1.18 | <0.001* | <0.001* |
| fGUPI6 | Need to urinate <2 hours after last urinating | 0–5 | 0.32 | 2.93 | 2.63 | <0.001* | 0.368 |
| fGUPI7 | Have your symptoms kept you from doing the kinds of things you would usually do | 0–3 | 0.00 | 0.98 | 0.70 | <0.001* | 0.181 |
| fGUPI8 | How much did you think about your symptoms | 0–3 | 0.03 | 1.80 | 1.98 | <0.001* | 0.392 |
| fGUPI9 | Satisfaction with current symptoms | 0–6 | 0.40 | 3.95 | 4.02 | <0.001* | 0.641 |
| POPDI-1 | Pressure in the lower abdomen | 0–4 | 0.02 | 0.33 | 0.18 | <0.001* | 0.036 |
| POPDI-2 | Heaviness or dullness in the lower abdomen | 0–4 | 0.03 | 0.22 | 0.17 | 0.003* | 0.244 |
| POPDI-3 | A bulge or something falling out that can see or feel in the vaginal area | 0–4 | 0.02 | 0.12 | 0.10 | 0.025* | 0.690 |
| POPDI-4 | A need to push on the vagina or around the rectum to have a complete bowel movement | 0–4 | 0.00 | 0.07 | 0.07 | 0.032* | 0.252 |
| POPDI-5 | A feeling of incomplete bladder emptying | 0–4 | 0.00 | 0.40 | 0.36 | <0.001* | 0.796 |
| POPDI-6 | A need to push up in the vagina area to start or complete urination | 0–4 | 0.00 | 0.02 | 0.02 | 0.268 | 0.432 |
| CRADI-8–1 | A need to strain too hard to have a bowel movement | 0–4 | 1.63 | 2.23 | 2.26 | 0.011* | 0.718 |
| CRADI-8–2 | A feeling that you have not completely emptied your bowels after a bowel movement | 0–4 | 0.16 | 0.40 | 0.36 | 0.007* | 0.862 |
| CRADI-8–3 | Losing stool without control when stools are well formed | 0–4 | 0.00 | 0.12 | 0.06 | 0.005* | 0.595 |
| CRADI-8–4 | Losing stool without control when stool is loose or liquid | 0–4 | 0.08 | 0.28 | 0.24 | 0.012* | 0.531 |
| CRADI-8–5 | Losing gas from the rectum without control | 0–4 | 0.15 | 0.39 | 0.45 | 0.005* | 0.789 |
| CRADI-8–6 | Pain with passing stools | 0–4 | 0.02 | 0.12 | 0.11 | 0.011* | 0.788 |
| CRADI-8–7 | A strong sense of urgency and have to rush to the bathroom to have a bowel movement | 0–4 | 0.15 | 0.39 | 0.35 | 0.005* | 0.805 |
| CRADI-8–8 | Stool passes through the rectum and bulges outside during or after a bowel movement | 0–4 | 0.00 | 0.08 | 0.02 | 0.030* | 0.356 |
| UDI-6–1 | Bothered by frequent urination | 0–4 | 0.02 | 2.03 | 2.06 | <0.001* | 0.929 |
| UDI-6–2 | Bothered by leakage related to feeling of urgency | 0–4 | 0.06 | 0.20 | 0.81 | 0.003* | <0.001* |
| UDI-6–3 | Bothered by leakage related to physical activity, coughing, or sneezing | 0–4 | 0.07 | 0.17 | 0.20 | 0.096 | 0.923 |
| UDI-6–4 | Bothered by small amounts of leakage (drops) | 0–4 | 0.05 | 0.37 | 0.56 | <0.001* | 0.042 |
| UDI-6–5 | Bothered by difficulty emptying bladder | 0–4 | 0.00 | 1.93 | 2.22 | <0.001* | 0.213 |
| UDI-6–6 | Bothered by pain or discomfort in the lower abdominal or genital area | 0–4 | 0.00 | 0.21 | 0.13 | <0.001* | 0.321 |
Uncorrected p-values from Mann Whitney U test presented.
*
= p-value was statistically significant after applying Benjamini-Hochberg false discovery rate (FDR) correction