TABLE 1.
Baseline Characteristics of Subjects With and Without Recurrent Colonization With MRSA
| Characteristic | Recurrent MRSA colonization (N = 85) | No recurrent MRSA colonization (N = 110) | P value |
|---|---|---|---|
| Age, mean (SD), y | 24.4 (0.65–79.5) | 23.1 (0.01–85.5) | .691 |
| Age <18 y | 41 (48.2) | 63 (57.3) | .210 |
| Percent of household members younger than 18, mean (SD) | 39.3 (0–100) | 30.1 (0–100) | .027 |
| Female sex | 53 (62.4) | 72 (65.5) | .654 |
| Race/ethnicity | .913 | ||
| White | 36 (42.4) | 42 (38.2) | |
| Black | 43 (50.6) | 58 (52.7) | |
| Hispanic | 1 (1.2) | 2 (1.8) | |
| Asian | 0 (0) | 3 (2.7) | |
| Mixed/Other | 2 (2.4) | 3 (2.7) | |
| Unknown/Refused | 3 (3.5) | 2 (1.8) | |
| Site of enrollment | .289 | ||
| HUP | 19 (22.4) | 27 (24.5) | |
| PPMC | 13 (15.3) | 12 (10.9) | |
| PAH | 2 (2.4) | 1 (0.9) | |
| CHOP | 34 (40.0) | 57 (51.8) | |
| HMC | 17 (20.0) | 13 (11.8) | |
| Medical setting | .986 | ||
| Emergency dept. | 58 (68.2) | 74 (67.3) | |
| Primary care | 22 (25.9) | 29 (26.4) | |
| Inpatient | 5 (5.9) | 7 (6.4) | |
| Comorbidities a | |||
| Hepatic dysfunction | 4 (4.7) | 5 (4.6) | >.99 |
| Renal dysfunction | 1 (1.2) | 1 (0.9) | >.99 |
| Diabetes mellitus | 5 (5.9) | 10 (9.2) | .394 |
| Malignancy | 2 (2.4) | 6 (5.5) | .470 |
| Organ transplant | 2 (2.4) | 0 (0.0) | .191 |
| Presenting SSTI b | |||
| Abscess | 77 (93.9) | 97 (90.7) | .413 |
| Incision and drainage performed | 53 (67.1) | 68 (65.4) | .809 |
| Household size | .189 | ||
| Single-person | 7 (8.2) | 11 (10.0) | |
| Two-person | 6 (7.1) | 14 (12.7) | |
| Three-person | 15 (17.6) | 17 (15.5) | |
| Four-person | 15 (17.6) | 31 (28.2) | |
| Five-person | 14 (16.5) | 15 (13.6) | |
| >5-person | 28 (32.9) | 22 (20.0) | |
| Colonization in at least 1 non-index household member | |||
| Total study period | 51 (60.0) | 54 (49.1) | .130 |
| First 14 days | 36 (42.4) | 33 (30.0) | .074 |
| Day 15 through termination of colonization | 16 (18.8) | 9 (8.2) | .028 |
| Termination of colonization to recurrence or end of follow-up | 48 (56.5) | 51 (46.4) | .162 |
NOTE. Data are number (%) unless otherwise specified. CHOP, Children’s Hospital of Philadelphia; HMC, Penn State Milton S. Hershey Medical Center; HUP, Hospital of the University of Pennsylvania; MRSA, methicillin-resistant Staphylococcus aureus; PAH, Pennsylvania Hospital; PPMC, Penn Presbyterian Medical Center; SSTI, skin and soft-tissue infection.
a
Percentages calculated using data available (194 subjects).
b
Percentages calculated using data available (189 subjects).