Table 2.
Changes in biochemical parameters during treatment with teriparatide.
| Basal | 6 months | 12 months | 18 months | 24 months | |
|---|---|---|---|---|---|
| PTH (pg/mL) | 44.5 ± 18.9 (n = 168) | 36.5 ± 19.2∗(n = 62) | 37.5 ± 19.0∗(n = 79) | 38.8 ± 18.6 (n = 35) | 42.9 ± 19.6 (n = 39) |
| Serum calcium (mg/dL) | 9.5 ± 0.5 (n = 245) | 9.8 ± 0.5∗(n = 168) | 9.6 ± 0.5∗(n = 198) | 9.7 ± 0.5∗(n = 103) | 9.7 ± 0.5∗(n = 72) |
| Urinary calcium (mg/24 h) | 149.8 ± 66.1 (n = 191) | 199.7 ± 106.2∗(n = 110) | 184.3 ± 117.5∗(n = 140) | 184.3 ± 117.5∗(n = 48) | 194.7 ± 124.0∗(n = 54) |
| Serum phosphate (mg/dL) | 3.8 ± 0.5 (n = 208) | 3.9 ± 0.6 (n = 127) | 3.8 ± 0.6 (n = 156) | 3.8 ± 0.4 (n = 76) | 3.8 ± 0.6 (n = 53) |
| 25(OH) vitamin D (ng/mL) | 33.7 ± 12.7 (n = 178) | 30.7 ± 10.2 (n = 124) | 34.1 ± 10.5 (n = 142) | 34.2 ± 10.8 (n = 62) | 36.6 ± 12.7 (n = 57) |
| Serum magnesium (mg/dL) | 2.1 ± 0.2 (n = 139) | 1.9 ± 0.2∗(n = 85) | 1.9 ± 0.2∗(n = 89) | 1.9 ± 0.2∗(n = 53) | 1.9 ± 0.2∗(n = 53) |
| Serum uric acid (mg/dL) | 4.4 ± 1.0 (n = 73) | 5.5 ± 1.1∗(n = 40) | 5.3 ± 1.2∗(n = 54) | 5.2 ± 1.4∗(n = 36) | 4.9 ± 1.4∗(n = 19) |
Mean ± SD. ∗Indicates significant differences vs. basal.