Table 4.
Association Between Rate of Quantitative Interstitial Abnormality Progression Between Visits 1 and 2 and All-Cause Mortality After Visit 2
| Cohort | Mortality (Hazard Ratio) |
|
|---|---|---|
| Effect,a Mean (95% CI) | P Value | |
| COPDGene | 1.69 (1.34-2.12) | < .001 |
| PLuSS | 1.28 (1.10-1.49) | .001 |
Adjusted for age; sex; self-reported race; baseline: quantitative interstitial abnormalities, emphysema, airway wall thickness (COPDGene only), smoking status, pack-years, BMI, and FEV1; and change in: emphysema, smoking status (COPDGene only), BMI, FEV1, and scanner manufacturer. COPDGene = Genetic Epidemiology of COPD; PLuSS = Pittsburgh Lung Screening Study.
a
Effect expressed as the association between the annual rate of change (percent per year) in quantitative interstitial abnormalities and the hazard ratio for all-cause mortality.