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. 2022 Nov 25;42(4):259–277. doi: 10.1038/s41388-022-02529-x

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Fig. 2 — Protein expression data for in vitro studies was extracted into a data table and entered into R to develop a summary heatmap of expression grouped by distinct model. Proteins are organised from most (top) to least (bottom) investigated across different models. Models are ordered by the MAP agent used for generation. (Blue) Downregulated, (Red) Upregulated, (Grey) Unchanged with respect to each models’ corresponding parental cell line, (Black) unknown or ambiguous result signifying an area of potential research interest (number of studies = 13).