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. 2023 Jan 20;13:1171. doi: 10.1038/s41598-023-27518-2

Table 3.

Tumor volume change between the baseline and C4 MRI for the development, retrospective independent testing, and prospective blinded testing groups.

Groups Tumor volume change (cm3) Percentage change (%)
pCR patients Non-pCR patients p pCR patients Non-pCR patients p
Development − 11 ± 13 − 16 ± 21 0.11 − 89 ± 10 − 69 ± 28 < 0.01
Testing (R) − 12 ± 8 − 24 ± 56 0.40 − 92 ± 14 − 70 ± 26 < 0.01
Testing (P) − 13 ± 16 − 13 ± 18 0.93 − 89 ± 26 − 61 ± 30 < 0.01

pCR pathological complete response, Development patients for model training and validation, Testing (R) retrospective independent testing, Testing (P) prospective blinded testing.