Table 3.

Tumor volume change between the baseline and C4 MRI for the development, retrospective independent testing, and prospective blinded testing groups.

Groups	Tumor volume change (cm3)			Percentage change (%)
	pCR patients	Non-pCR patients	p	pCR patients	Non-pCR patients	p
Development	− 11 ± 13	− 16 ± 21	0.11	− 89 ± 10	− 69 ± 28	< 0.01
Testing (R)	− 12 ± 8	− 24 ± 56	0.40	− 92 ± 14	− 70 ± 26	< 0.01
Testing (P)	− 13 ± 16	− 13 ± 18	0.93	− 89 ± 26	− 61 ± 30	< 0.01

pCR pathological complete response, Development patients for model training and validation, Testing (R) retrospective independent testing, Testing (P) prospective blinded testing.