Table 2.
Imaging features of CCM detected at first brain MRI and with symptomatic hemorrhage identified at diagnosis and follow-up
|
CCM identified at first brain MRI n = 587 | |
| Location, n (%) | |
| Cerebral lobes | 492 (83.8) |
| Nucleocapsular/Thalamic | 23 (3.9) |
| Brainstem | 27 (4.6) |
| Cerebellum | 39 (6.6) |
| Intra-ventricular | 6 (1.0) |
| Modified Zabramski type, n (%) | |
| I | 20 (3.4) |
| II | 116 (19.8) |
| III | 79 (13.5) |
| IV | 362 (61.7) |
| V | 10 (1.7) |
| Size in mm (except type IV CCM), median (IQR) | 7.0 (1–52) |
| Giant lesions | 5 (0.9) |
|
CASH identified at diagnosis and follow-up n = 23 | |
| Location, n (%) | |
| Cerebral lobes | 14 (61.0) |
| Nucleocapsular/thalamic | 1 (4.4) |
| Brainstem | 5 (21.7) |
| Cerebellum | 2 (8.7) |
| Spinal cord | 1 (4.4) |
| Modified Zabramski type, n (%) | |
| I | 6 (26.1) |
| V | 17 (73.9) |
| Size in mm, median (IQR; range) | 27 (25;8–52) |
| Multilocular morphology, n (%) | 12 (52.2) |
| Hemossiderin ring, n (%) | 15 (65.2) |
| Fluid–fluid levels, n (%) | 13 (56.5) |
| T1 hyperintense perilesional sign, n (%) | 15 (65.2) |
| Perilesional edema, n (%) | 16 (69.6) |
| Associated DVA | 0 (0.0) |
Legend: CASH, cavernous angioma with symptomatic hemorrhage; DVA, developmental venous anomaly; FU, follow-up; IQR, interquartile range