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. 2023 Jan 12;112(2):197–217. doi: 10.1007/s00223-022-01054-z
The group recommends the optional use of adiponectin during both phase II and phase III studies at baseline and during the whole follow-up to evaluate the contributing processes linking adipose tissue and sarcopenia. Changes in BMI, muscle density and any body composition measure should absolutely be integrated in the statistical analysis, as these changes can confound the association between adiponectin and sarcopenia factors [104]