Table 4.

Immunofluorescence patterns of anti-nuclear antibodies (ANA) in patients with Graves’ disease (GD) or toxic nodular goiter

ANA pattern	GD (n = 212)	TNG (n = 71)	Statistics
Nuclear
Speckled	29 (13.6)	0 (0)	OR: 22.9, 95% CI from 1.3 to 381.3 P = 0.028
Homogenous	31 (14.6)	14 (19.7)	OR: 0.6, 95% CI from 0.3 to 1.4 P = 0.31
Dense fine speckled	35 (16.5)	19 (26.7)	OR: 0.5, 95% CI from 0.2 to 1 P = 0.059
Fine speckled/fine granular	81 (38.2)	27 (38)	OR: 1, 95% CI from 0.5 to 1.7 P = 0.97
Large coarse speckled	11 (5.1)	0 (0)	OR: 8.1, 95% CI from 0.4 to 140.2 P = 0.97
Nucleolar	14 (6.6)	5 (7)	OR: 0.9, 95% CI from 0.3 to 2.6 P = 0.89
Cytoplasmic	6 (2.8)	3 (7)	OR: 1.2, 95% CI from 0.3 to 5.3 P = 0.73
Centromere	1 (0.4)	1 (1.4)	OR: 0.3, 95% CI from 0 to 5.3 P = 0.43
Mitotic spindle	4 (1.8)	2 (2.8)	OR: 0.6, 95% CI from 0.1 to 3.7 P = 0.63

Data are n (%)