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. 2022 Dec 28;97(2):523–545. doi: 10.1007/s00204-022-03436-6

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Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — mRNA baseline expression of untreated samples for genes potentially involved in the biotransformation of TCE after glutathione conjugation. GGT activity: γ-glutamyltransferase (GGT1) and γ-glutamyl leukotrienase (GGT5), Dipeptidase activity: cysteinylglycine-S-Conjugate Dipeptidase (LAP3), β-lyase activity: kynurenine aminotransferase 3 (KYAT3), branched chain amino acid transaminase 1 (BCAT1) and FMO activity: flavin containing dimethylaniline monoxygenase 3 (FMO3). Genes are colour coded by cell model as shown in Fig. 2