Table 2.

PACC Neuropsychological Test Components Per Cohort

Domain	ADNI	HABS	AIBL	A4
Global	Total MMSE score	Total MMSE score	Total MMSE score	Total MMSE score
Story recall memory	Logical memory delayed recall (Anna Thompson story)	Logical memory delayed recall (Anna Thompson story)	Logical memory delayed recall (Anna Thompson story)	Logical memory delayed recall (Robert Miller story)
Executive function	Trails B time	Digit Symbol Substitution Test (WAIS-R; 90 s)	Digit Symbol Substitution Test (WAIS-III; 120 s)	Digit Symbol Substitution Test (WAIS-R; 90 s)
Verbal fluency	Category fluency—animals	Category fluency—animals + vegetables + fruits	Category fluency—animals + furniture + names
List learning Memory	ADAS-cog del word recall	Free and Cued Selective Reminding Test (FCSRT)	California Verbal Learning Test—2nd Ed. (CVLT-II, long delay)	Free and Cued Selective Reminding Test (FCSRT)

Note. Bolded tests reflect cohort shared tests between studies that share recoding distribution and confirmatory factor analysis (CFA) loadings and thresholds (MMSE in all studies; logical memory delayed recall and the animals category in ADNI, HABS, and AIBL; WAIS-R and FCSRT in HABS and A4). Means and standard deviations (SD) are provided under the MMSE and logical memory scores for ADNI, AIBL, and HABS to demonstrate differences across the cohorts. PACC = preclinical Alzheimer cognitive composite; ADNI = Alzheimer’s Disease Neuroimaging Initiative; HABS = Harvard Aging Brain Study; AIBL = Australian Imaging, Biomarker and Lifestyle Study of Ageing; A4 = Anti-Amyloid Treatment of Asymptomatic Alzheimer’s Disease; MMSE = Mini-Mental State Examination; WAIS-R = Wechsler Adult Intelligence Scale-Revised; WAIS-III = Wechsler Adult Intelligence Scale-III; ADAS = Alzheimer’s disease Assessment Scale; CVLT = California Verbal Learning Test.