Table 1:

Cell behavior regulated by secreted factors in the model. The up arrow indicates activation and the down arrow represents inhibition by these regulated factors.

	Regulating Factors
Cell Behavior	IL-1β	TNFα	GM-CSF	MMP-9	TGFβ
Cardiomyocyte cell death	↑	↑			↓
Neutrophil infiltration	↑		↑		↓
Neutrophil removal		↓		↓
Monocyte infiltration	↑		↑
Monocyte removal		↓		↓
Macrophage differentiation	↑		↑
Macrophage proliferation		↑	↑		↑
Macrophage removal		↓		↓
Macrophage phagocytosis		↓		↑	↑
IL-1β secretion by macrophages					↓
TNFα secretion by macrophages					↓
TGFβ secretion by macrophages					↑
Fibroblast proliferation					↑
TNFα secretion by fibroblasts					↓
MMP-9 secretion by fibroblasts					↑
TGFβ secretion by fibroblasts					↑
Pro-collagen secretion by fibroblasts					↑
Collagen maturation				↓