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. 2001 Aug;69(8):5056–5063. doi: 10.1128/IAI.69.8.5056-5063.2001

FIG. 1.

FIG. 1

H. pylori infection, chronic gastritis, apoptosis, and proliferation in stomachs of H. pylori-infected mice. (A) Light microscopic photograph of gastric tissue from a C57BL/6 mouse colonized with H. pylori SS1 showing the S shape of the bacteria. H. pylori infections were confirmed by Giemsa staining in all cases of H. pylori-inoculated mice (magnification ×730). (B) Findings of chronic gastritis with many inflammatory cells in the stomach of an H. pylori-infected mouse (H&E, ×292). (C) Increased positive apoptotic epithelial cells in the superficial portion of the stomach of an H. pylori-infected mouse (TUNEL stain, ×292). (D) Increased numbers of positive apoptotic epithelial cells in the proliferation compartment and superficial portion of the antral mucosa of the stomach of an H. pylori-infected mouse (TUNEL stain, ×292). (E and F) Increased number of Ki67-positive cells in the proliferation compartment of the body (E) and antrum (F) of the stomach of an H. pylori-infected mouse (Ki67 immunostain, ×292).