Figure 1.

Curation of scRNA-seq datasets generated from the mature retinal tissue

(A) Schematic of single-cell transcriptomic profiling by scRNA-seq and the major cell types of the human retina.

(B) Summary of scRNA-seq datasets collected from the mature retinal tissues.

(C) UMAP representation of the transcriptomes of single cells. Cells are colored by their type (left), dataset of origin (middle), and batch in each dataset (right). Abbreviations: MG, Muller glial; RGC, retinal ganglion cell; RPE, retinal pigment epithelium.

(D) Proportions of cell types (color coded) and total number of cells in each batch and dataset.

(E) Expression patterns of known retinal cell-type marker genes across datasets and batches. As in (C), the color annotation denotes dataset and batch information.