Table 3.
The survival fraction of U87 and U251 cells after X–ray irradiation whether HIF1A was knocked down under normoxia and hypoxia for 16 h.
| SFa (Mean±SEMb) | 2Gy | 4Gy | 6Gy | 8Gy | |
|---|---|---|---|---|---|
| U87 | Normoxia, KDc | 0.28 ± 0.03 | 0.09 ± 0.02 | 0.03 ± 0.01 | 0.01 ± 0.00 |
| Hypoxia, KD | 0.49 ± 0.04 | 0.30 ± 0.04 | 0.15 ± 0.02 | 0.09 ± 0.01 | |
| Normoxia, MOCK | 0.33 ± 0.02 | 0.12 ± 0.01 | 0.02 ± 0.00 | 0.01 ± 0.00 | |
| Hypoxia, MOCK | 0.67 ± 0.04 | 0.48 ± 0.05 | 0.23 ± 0.01 | 0.09 ± 0.01 | |
| U251 | Normoxia, KD | 0.52 ± 0.05 | 0.21 ± 0.01 | 0.07 ± 0.00 | 0.02 ± 0.00 |
| Hypoxia, KD | 0.60 ± 0.00 | 0.27 ± 0.01 | 0.11 ± 0.01 | 0.04 ± 0.01 | |
| Normoxia, MOCK | 0.57 ± 0.03 | 0.22 ± 0.00 | 0.08 ± 0.01 | 0.02 ± 0.00 | |
| Hypoxia, MOCK | 0.80 ± 0.04 | 0.36 ± 0.00 | 0.18 ± 0.02 | 0.06 ± 0.01 |
a: survival fraction; b: standard error of the mean; c: knockdown