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. Author manuscript; available in PMC: 2023 Dec 13.
Published in final edited form as: J Am Coll Cardiol. 2022 Nov 2;80(24):e223–e393. doi: 10.1016/j.jacc.2022.08.004

TABLE 22.

Signs and Symptoms of AAS

Clinical Signs and Symptoms Cause
Asymmetric blood pressure (>20 mm Hg) between limbs Compromise of branch artery flow
Bowel ischemia or gastrointestinal bleed Malperfusion of the celiac or superior mesenteric artery
Dysphagia Compression of the esophagus
Dyspnea Compression of trachea or bronchus, congestive heart failure from aortic regurgitation, or cardiac tamponade
Hemoptysis Vascular rupture into lung parenchyma
Hoarseness Compression recurrent laryngeal nerve
Horner’s syndrome Compression of sympathetic chain
Myocardial ischemia or myocardial infarction Coronary artery involvement by dissection or compression by aneurysm
New murmur of aortic regurgitation Incomplete aortic valve closure secondary to leaflet tethering by the dilated aorta or cusp prolapse because of dissection into the aortic root
Oliguria or hematuria (gross) Malperfusion of 1 or both renal arteries
Paraplegia Spinal malperfusion attributable intercostal artery involvement
Lower extremity ischemia Malperfusion of iliac artery
Shock Cardiac tamponade, hemothorax, frank aortic rupture, acute severe aortic regurgitation, severe myocardial ischemia
Shortness of breath Pericardial effusion, congestive heart failure from acute severe aortic regurgitation, or hemothorax
Stroke symptoms Carotid or vertebral artery involved
Superior vena cava syndrome Compression of the superior vena cava
Syncope Carotid artery involvement or cardiac tamponade

AAS indicates acute aortic syndrome.