Table 2.
Characterization of ELISA, Proteomics, and ImageStreamX for the analysis of circulating histones and histone complexes. The advantages and disadvantages of the indicated parameters are illustrated through an asterisk-based system.
| Detection Method |
Sensitivity | Multiplex | Bias | Easy to Use |
Easy to Access |
Expensiveness | Speed |
|---|---|---|---|---|---|---|---|
| ELISA | **** | ** | **** | **** | *** | **/*** | ** |
| Proteomics | **** | **** | * | * | * | * | ** |
| ImageStream | **** | *** | *** | **/*** | * | **/*** | **** |
*—low; **—low to moderate; ***—moderate to high; ****—high.