Table 1.
Age (years) at Time of Delivery a | 5.2 ± 36.5 |
Parity a | 0.9 ± 1 |
Pregestational BMI a | 3 ± 23 |
Multiple gestation b | (27) 18/5 |
ICP in previous pregnancy b | (44) 18/8 |
IUFD in previous pregnancy due to ICP b | (5.5) 18/1 |
Gestational diabetes b | 6/18 (33) |
Gestational age at diagnosis (wks.) a | 5 ± 32 |
TBA at diagnosis a (µmol/L) (range) | (94−12) 3 ± 33.4 |
Gestational age at UDCA administration | 33 ± 5.7 |
Length of treatment (days) a | 29 ± 44 (2−133) |
Maximal TBA a (µmol/L) (range) | 99.6 ± 46 (51−247) |
Second line therapy | 6/18(33) |
Maternal TBA at delivery a (µmol/L) (range) | 76.4 ± 30.3 (40−129) |
Maternal TBA at delivery >90 µmol/L. b | 4/18(22) |
Gestational age at delivery (wks.) a | 35.6 ± 1.6 |
Delivery < 37 wks. b | 16/18 (88) |
Delivery < 34 wks. b | 3/18 (17) |
Spontaneous delivery b | 1/18 (5.5) |
Cesarean section b | 5/18 (27) |
a Data are presented as mean ±SD. b Data are presented as n (%). BMI—Basic Metabolic Index, IUFD-intrauterine fetal demise, ICP-intrahepatic cholestasis of pregnancy, UDCA-Ursodeoxycholic acid, TBA—Total bile acids, UDCA ursodeoxycolic acid.