Skip to main content
. 2023 Jan 16;11(1):85. doi: 10.3390/toxics11010085

Figure 4.

Figure 4

ERRBS in weanling offspring mouse hearts. (A) Numbers of differentially hyper- and hypomethylated cytosines (DMCs) and regions (DMRs) in male and female hearts. (B,C) Volcano plots depicting DMCs in males and females. CpGs with FDR <0.05 and at least 10% absolute change in DNA methylation were considered significant. (D,E) Annotation summary plots depicting the total number of CpGs tested in pink, hypermethylated DMCs in green, and hypomethylated DMCs in blue for each genomic annotation using the R annotatr package for males (D) and females (E).