Figure 4.
Modulation of intracellular protein expression (IL-1β, IL-6, and LIF) in Tha- and Th2P-4M-infected glial cells. (A) Intracellular protein concentrations of SK-N-SH cells upon Tha or Th2P-4M infection. (B) Intracellular protein concentrations of hiNeurons upon Tha or Th2P-4M infection. (C) Intracellular protein concentrations of astrocyte-like SVGp12 cells upon Tha or Th2P-4M infection. (D) Intracellular protein concentrations of foetal pAstrocytes upon Tha or Th2P-4M infection. (E) Intracellular protein concentrations of microglia-like HMC3 cells upon Tha or Th2P-4M infection. (A–E) Cells were infected with Tha or Th2P-4M (MOI 5), and intracellular protein concentration was quantified at 48 h post-infection using the DropArray system (Curiox). All experiments were performed three times (n = 3) independently. All bars show mean ± SD with a one-way ANOVA analysis. To correct for multiple testing, the p-value was corrected accordingly. If no p-value is indicated, no significant difference was observed.